- Due to his role of Kurgan in Highlander (1986), his voice was featured on the Queen song "Gimme the Prize (Kurgan's Theme)". An alternate version appeared in the film itself, but samples of his voice are included on the 1986 studio album "A Kind of Magic".
- In 1999, he spearheaded a charity campaign to raise funds for J. Madison Wright, the young girl who played his screen daughter on the television series Earth 2 (1994). Madison, then aged 15, had developed cardiomyopathy and was in dire need of a heart transplant, a very costly operation which exceeded her family's lifetime health insurance policy. Clancy offered to assist the Wrights in their plight. He also bought young Madison a laptop computer for Christmas in 1999. Tragically, Madison died seven years later, in July 2006, of a heart attack.
- Both his grandfather (Clarence J. Brown) and father (Clarence J. Brown Jr.) were United States Representatives from the 7th District of Ohio. Clarence J. Brown served from 1939-65 and Clarence J. Brown Jr. from 1965-83. Both men also ran, unsuccessfully, for governor of Ohio.
- Describes himself as an avid reader who particularly enjoys the works of Frank Herbert.
- Is a patron of the Beth Brown Memorial Fund, a scholarship programme designed to assist poorer students who wish to study in the field of paediatric healthcare. The charity is in honour of his elder sister who died in childhood of leukaemia in 1964. It has since expanded to also offer the Clarence J. Brown Scholarship for students interested in pursuing careers in government and public service as well as the Robert Townsley Scholarship for students of journalism.
- Claims to have been introduced to acting by a neighbor who got him into William Shakespeare at a young age.
- Was hospitalized after becoming sick from the prosthetic make up he wore as Viktor in The Bride (1985). He was reluctant to don prosthetics for his role in Highlander (1986).
- Originally auditioned for the role of Superman/Clark Kent on Bruce Timm's Superman: The Animated Series (1996), but Timm felt his voice was better suited to Lex Luthor, bringing the archvillain a smooth combination of menacing brute and charming manipulator. Tim Daly was then cast as Superman/Clark Kent instead.
- For Highlander (1986), he said that he made lifelong friends with Bob Anderson, the swordmaster for that film as well as the original Star Wars trilogy. He said if he had not been an actor, he would have been (in order) a fireman, an aristocrat, an archaeologist/anthropologist, a scuba diver and a circus acrobat.
- Has played the same character (Lex Luthor) on four different series: Superman: The Animated Series (1996), Justice League (2001), The Batman (2004) and The Life and Times of Juniper Lee (2005).
- On August 20, 2002, he was named chairman of the board of the Ohio-based Brown Publishing Company, a newspaper company owned by his family and founded by his grandfather. The company went out of business in 2010.
- Collects animation art.
- According to the trivia track on the DVD of The Adventures of Buckaroo Banzai Across the 8th Dimension (1984), his character, Rawhide, did not die but went into a deep coma, and that he was expected to recover very soon.
- First acted on stage during a 7th grade school play of "The Mouse That Roared".
- Although his character Rawhide dies in The Adventures of Buckaroo Banzai Across the 8th Dimension (1984), he is still under contract to appear in a sequel to the film.
- Has three times played senior prison officers in movies dealing with miscarriages of justice: in The Shawshank Redemption (1994), the tyrannical Captain Hadley; in The Hurricane (1999), the sympathetic Lt. Williams; and in Last Light (1993) as Lt. McMannis.
- Despite portraying a centuries-old sword-master in "Highlander" and a space-age drill instructor in "Starship Troopers", Brown insists he's not a true martial artist..."Not unless you count wrestling with my daughter when she was a kid," he chuckles.
- Originally attended Northwestern University on a track scholarship as a discus-thrower, but switched majors to Theater Arts after two seasons. His fraternity is Sigma Chi.
- Has played villains for two of DC Comics' most famous characters. He voiced Superman's nemesis Lex Luthor and the Green Lantern's adversary Parallax.
- Both he and Highlander (1986) co-star Christopher Lambert have portrayed the Mortal Kombat character Rayden. Lambert played Rayden in the film Mortal Kombat (1995), while Brown portrayed Rayden on the television series Mortal Kombat: Defenders of the Realm (1995).
- Has played two characters named Captain Hadley: The Guardian (2006) and The Shawshank Redemption (1994).
- Designated as a Significant Sig by the Sigma Chi General Fraternity in 2010.
- Appeared in Desert Crossing (2002) and was the voice of 'ch0526374' in Star Wars: Rebels (2014), making him one of only three actors to appear in both the Star Trek and Star Wars franchises. The others are Brent Spiner and Simon Pegg.
- Daughter Rose Beth Brown (born in October 1995). He also has a son born in 2003.
- Is a Republican, but a moderate by today's standards.
- Has thrice played inmates: Bad Boys (1983), Legacy (2015), & Afterlife (1996). In The Shawshank Redemption (1994), he was a prison guard.
- Is a fan of John Wayne's movies.
- Profiled in "Character Kings: Hollywood's Familiar Faces Discuss the Art & Business of Acting" by Scott Voisin. (2009)
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