The Silence of the Lambs (1991)
Winner: Best Picture, Best Director, Best Actor, Best Actress, Best Adapted Screenplay
Woody Allen, James Cameron, Jonathan Demme, Oliver Stone, and several other prominent directors worked with Orion during its most successful years from 1978 to 1992.
Which is your favorite movie distributed by Orion Pictures and nominated for the Academy Awards?
Sources: Wikipedia and IMDb Search