Dorothy had the flu and 5 months later, she is always tired and knows something is wrong. She consults doctor after doctor, even going to New York to consult a specialist and they run every test available but still they know nothing. They suggest she might be lonely and to consult a psychiatrist, which she has and they say there is nothing wrong with her.
The final scene of the show is heart-breaking as Sophia is so very worried about losing her daughter and something is seriously wrong with her and she is dying.