Sort by Popularity - Most Popular Movies and TV Shows tagged with keyword "side-effect"
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1. A Beautiful Mind (2001)
PG-13 | 135 min | Biography, Drama, Mystery
A mathematical genius, John Nash made an astonishing discovery early in his career and stood on the brink of international acclaim. But the handsome and arrogant Nash soon found himself on a harrowing journey of self-discovery.
Director: Ron Howard | Stars: Russell Crowe, Ed Harris, Jennifer Connelly, Christopher Plummer
Votes: 987,545 | Gross: $170.74M
2. Painkiller (2023)
TV-MA | 48 min | Crime, Drama
The causes and consequences of America's opioid epidemic unfold in this drama following its perpetrators, victims and an investigator seeking the truth.
Stars: Uzo Aduba, Matthew Broderick, Taylor Kitsch, Dina Shihabi
Votes: 30,367
3. Akira (1988)
R | 124 min | Animation, Action, Drama
A secret military project endangers Neo-Tokyo when it turns a biker gang member into a rampaging psychic psychopath who can only be stopped by a teenager, his gang of biker friends and a group of psychics.
Director: Katsuhiro Ôtomo | Stars: Mitsuo Iwata, Nozomu Sasaki, Mami Koyama, Tesshô Genda
Votes: 205,420 | Gross: $0.55M
4. Side Effects (I) (2013)
R | 106 min | Crime, Drama, Mystery
A young woman's world unravels when a drug prescribed by her psychiatrist has unexpected side effects.
Director: Steven Soderbergh | Stars: Rooney Mara, Channing Tatum, Jude Law, Catherine Zeta-Jones
Votes: 197,186 | Gross: $32.17M
5. Scanners (1981)
R | 103 min | Horror, Sci-Fi, Thriller
A scientist trains a man with an advanced telepathic ability called "scanning" to stop a dangerous Scanner with extraordinary psychic powers from waging war against non scanners.
Director: David Cronenberg | Stars: Jennifer O'Neill, Stephen Lack, Patrick McGoohan, Lawrence Dane
Votes: 61,798 | Gross: $14.23M
6. Flatliners (2017)
PG-13 | 109 min | Drama, Horror, Mystery
Five medical students, obsessed by what lies beyond the confines of life, embark on a daring experiment: by stopping their hearts for short periods, each triggers a near-death experience - giving them a firsthand account of the afterlife.
Director: Niels Arden Oplev | Stars: Elliot Page, Diego Luna, Nina Dobrev, James Norton
Votes: 50,992 | Gross: $16.88M
7. Max Payne (2008)
PG-13 | 100 min | Action, Crime, Drama
Coming together to solve a series of murders in New York City are a police detective and an assassin, who will be hunted by the police, the mob, and a ruthless corporation.
Director: John Moore | Stars: Mark Wahlberg, Mila Kunis, Beau Bridges, Ludacris
Votes: 130,209 | Gross: $40.69M
8. The East (2013)
PG-13 | 116 min | Adventure, Crime, Drama
An operative for an elite private intelligence firm finds her priorities changing dramatically after she is tasked with infiltrating an anarchist group known for executing covert attacks upon major corporations.
Director: Zal Batmanglij | Stars: Brit Marling, Alexander Skarsgård, Elliot Page, Toby Kebbell
Votes: 52,400 | Gross: $2.27M
9. Old Dogs (I) (2009)
PG | 88 min | Comedy, Family
Two friends and business partners find their lives turned upside-down when strange circumstances lead them to be the temporary guardians of 7-year-old twins.
Director: Walt Becker | Stars: Robin Williams, John Travolta, Seth Green, Kelly Preston
Votes: 39,582 | Gross: $49.49M
10. Body Bags (1993 TV Movie)
R | 94 min | Comedy, Horror, Sci-Fi
Three short stories in the horror genre: the first about a serial killer, the second about a hair transplant gone wrong, and the third about a baseball player.
Directors: John Carpenter, Tobe Hooper, Larry Sulkis | Stars: John Carpenter, Tom Arnold, Tobe Hooper, Robert Carradine
Votes: 12,618
11. Prey (2017 Video Game)
M | Action, Adventure, Horror
Morgan Yu is trapped aboard a space station filled with shape-shifting aliens with no memory of how he got there. Guided by a mysterious stranger and his former self, he must set the station's self-destruct before the aliens reach Earth.
Director: Raphael Colantonio | Stars: Walton Goggins, Benedict Wong, Mae Whitman, James Hong
Votes: 2,279
12. Fedora (1978)
PG | 114 min | Drama, Romance
Down-on-his-luck Hollywood producer Barry 'Dutch' Detweiler attempts to lure Fedora, a famous but reclusive film actress, out of retirement only to discover the horrible truth behind her success.
Director: Billy Wilder | Stars: William Holden, Marthe Keller, Hildegard Knef, José Ferrer
Votes: 5,189 | Gross: $2.20M
13. Dr. Jekyll and Ms. Hyde (1995)
PG-13 | 90 min | Comedy, Romance, Sci-Fi
A scientist creating perfumes inherits his great grandfather Dr. Jekyll's formula and decides to use modern technology to improve it. He ends up as an ambitious, ruthless woman. She tries to prevent returning into the spineless man.
Director: David Price | Stars: Sean Young, Tim Daly, Lysette Anthony, Stephen Tobolowsky
Votes: 3,022 | Gross: $2.76M
14. The Coed and the Zombie Stoner (2014)
Unrated | 91 min | Comedy, Horror, Sci-Fi
When a nerdy sorority girl falls in love with a zombie, it's only a matter of time before a zombie apocalypse is unleashed on campus. The sorority girl discovers that weed is the cure--now ... See full summary »
Director: Glenn Miller | Stars: Catherine Annette, Grant O'Connell, Jamie Noel, Aaron Caleb
Votes: 1,579
15. Body Parts (1991)
R | 88 min | Horror, Sci-Fi, Thriller
After losing his arm in a car accident, a criminal psychologist has it replaced with a limb that belonged to a serial killer.
Director: Eric Red | Stars: Jeff Fahey, Lindsay Duncan, Kim Delaney, Zakes Mokae
Votes: 5,022 | Gross: $9.19M
16. The Invisible Woman (1940)
Approved | 72 min | Comedy, Romance, Sci-Fi
An attractive model with an ulterior motive volunteers as guinea pig for an invisibility machine.
Director: A. Edward Sutherland | Stars: Virginia Bruce, John Barrymore, John Howard, Charles Ruggles
Votes: 3,358
17. College Coeds vs. Zombie Housewives (2015 Video)
TV-MA | 81 min | Comedy, Horror, Romance
Efforts to develop a new sexual enhancement formula go terribly wrong when the beautiful test subjects lapse into a trance-like state.
Director: Dean McKendrick | Stars: Karlie Montana, Frankie Dell, Mary Carey, Andrew Espinoza Long
Votes: 188
18. Seventeen Again (2000 TV Movie)
TV-G | 97 min | Comedy, Family, Fantasy
While divorced and bickering grandparents watch their grandchildren, a lab experiment gone awry transforms the elders into teenagers again.
Director: Jeffrey W. Byrd | Stars: Tia Mowry, Tamera Mowry-Housley, Mark Taylor, Tahj Mowry
Votes: 3,235
19. Kids in the Hall: Brain Candy (1996)
R | 89 min | Comedy
A pharmaceutical scientist creates a pill that makes people remember their happiest memory, and although it's successful, it has unfortunate side effects.
Director: Kelly Makin | Stars: David Foley, Bruce McCulloch, Kevin McDonald, Mark McKinney
Votes: 9,481 | Gross: $2.65M
20. Cold Souls (2009)
PG-13 | 101 min | Comedy, Drama, Fantasy
Paul is an actor who feels bogged down by his participation in a production of Chekov's play, Vanya.
Director: Sophie Barthes | Stars: Paul Giamatti, Emily Watson, Dina Korzun, Armand Schultz
Votes: 10,228 | Gross: $0.90M
21. Tell Me How I Die (2016)
Not Rated | 107 min | Horror, Mystery, Thriller
A9913 is a new drug improving memory - like being there again. Anna joins 17 others testing it for $2000. Some experience the near future including deaths.
Director: D.J. Viola | Stars: Nathan Kress, Virginia Gardner, Kirby Bliss Blanton, Ryan Higa
Votes: 5,304
22. Advantageous (2015)
Not Rated | 90 min | Drama, Family, Sci-Fi
In a near-future city where soaring opulence overshadows economic hardship, Gwen and her daughter Jules do all they can to hold on to their joy together, despite the instability surfacing in their world.
Director: Jennifer Phang | Stars: Jacqueline Kim, James Urbaniak, Freya Adams, Ken Jeong
Votes: 5,968
23. Tetsuo: The Bullet Man (2009)
Not Rated | 71 min | Action, Horror, Sci-Fi
Losing his son Tom in a hit and run triggers violent emotions in Anthony, whose body begins to transform. When the driver who killed Tom reappears, Anthony mutates into a mass of metal - a human weapon fuelled by an uncontrollable rage.
Director: Shin'ya Tsukamoto | Stars: Eric Bossick, Akiko Monô, Yûko Nakamura, Stephen Sarrazin
Votes: 2,212
24. Keith Lemon: The Film (2012)
85 min | Comedy
Keith Lemon (Leigh Francis) is preparing to take his invention, the securipole, which he has been attempting to lift off the ground for twenty years, to a business convention in London. ... See full summary »
Director: Paul Angunawela | Stars: Leigh Francis, Kelly Brook, Laura Aikman, Kevin Bishop
Votes: 4,359
25. Unedited Footage of a Bear (2014 TV Short)
16+ | 10 min | Short, Horror, Thriller
Short film that starts as footage of a grizzly bear and is then interrupted by a commercial for a drug called "Claridryl." The protagonist talks about the drug. But it quickly becomes clear that something is very wrong.
Directors: Ben O'Brien, Alan Resnick | Stars: Kerry Donelli, Jacqueline Donelli, Jackson Manning, Jamie Norcross
Votes: 1,985
26. Zanox (2022)
89 min | Comedy, Crime, Romance
As a result of a drug experiment, Misi will be able to travel through time, but only if he drinks from a special homemade spirit.
Director: Gábor Benö Baranyi | Stars: Elõd Bálint, Lili Erdõs, András Hatházi, Kati Sólyom
Votes: 1,459
27. Bigger Stronger Faster* (2008)
PG-13 | 105 min | Documentary, Sport
An examination of America's win-at-all-cost culture from the perspective of bodybuilding and performance enhancing drugs, as it focuses on a pair of siblings chasing their dream.
Director: Chris Bell | Stars: Chris Bell, Mike Bell, Mark Bell, Hank Aaron
Votes: 13,817 | Gross: $0.31M
28. Sexual Chemistry (1999)
R | 97 min | Comedy, Sci-Fi
At Biotec the scientists are trying to develop a sexually stimulating drug for both men and women. Robert tries his on himself and it turns him on and off into a sexy woman and back to himself making things complicated.
Director: Mike Sedan | Stars: Jeff Xander, Stephanee LaFleur, Chanda Marie, Raisa Ivanic
Votes: 315
29. Fair Play (2014)
100 min | Drama, Sport
The 1980s in Czechoslovakia. The young talented sprinter Anna (Judit Bárdos) is selected for the national team and starts training to qualify for the Olympic Games. As a part of the ... See full summary »
Director: Andrea Sedlácková | Stars: Judit Bárdos, Anna Geislerová, Roman Luknár, Eva Podzimková
Votes: 1,097
30. SideFX (2004)
R | 85 min | Horror
Sex, drugs, and rock-and-roll will never be the same after a medieval sex drug makes a comeback on the college party scene. Everyone wants to try this "orgasm" drug but no one considers the... See full summary »
Director: Patrick Johnson | Stars: Amanda Phillips, Todd Swift, Amber Heard, Aaron Garrett
Votes: 806
31. Zombie for Sale (2019)
Not Rated | 112 min | Comedy, Horror, Sci-Fi
When a pharmaceutical company's illegal experiments inadvertently create a zombie, the strange Park family finds it and tries to profit from it.
Director: Lee Min-jae | Stars: Jeong Jae-yeong, Kim Nam-gil, Uhm Ji-won, Lee Soo-kyung
Votes: 2,518
32. The Drug Trial: Emergency at the Hospital (2017 TV Movie)
58 min | Documentary, Drama
Docu-drama telling the story of one of the most infamous incidents in recent British medical history. On 13th March 2006, 8 healthy young men took part in a clinical trial for a leukaemia drug that went very wrong.
Director: Barbie MacLaurin | Stars: Philip Buck, Nadim Khan, Arun Daniel, Leo Hunter
Votes: 52
33. The Wife of Seishu Hanaoka (1967)
99 min | Drama, History
The Wife of Seishû Hanaoka is set in feudal Japan. Its two central characters are based on the wife and mother of Japanese physician Seishû Hanaoka (1760-1835). Hanaoka developed a herbal ... See full summary »
Director: Yasuzô Masumura | Stars: Raizô Ichikawa, Ayako Wakao, Hideko Takamine, Yûnosuke Itô
Votes: 222
34. De zeemeerman (1996)
111 min | Comedy, Fantasy, Romance
Tony is really handsome, but he smells. A scientist gives him a potion that should get rid of his fishy smell. Unfortunately, there are some serious side effects.
Director: Frank Herrebout | Stars: Daniël Boissevain, Gonny Gaakeer, Angelique de Bruijne, Frans van Deursen
Votes: 538
35. Vaccine Nation (2008)
140 min | Documentary
This Gary Null, Ph.D. documentary challenges the assumption that vaccines are PERFECTLY safe. The use of heavy metals such as mercury, connections to autism and the high number of vaccines ... See full summary »
Director: Gary Null
Votes: 84
36. Sci-Fi Harry (2000–2001)
Animation, Drama, Horror
A bullied shy awkward teenage slowly gains mysterious psychic powers leading him into a dark conspiracy involving a clandestine organization with lethal and frightening consequences for all.
Votes: 31
37. Splhající profesor (1992 TV Movie)
51 min | Comedy, Crime, Horror
Why does the esteemed Professor Presbury sometimes act like a lunatic? Does his climbing mania have something to do with the late passion with which he developed for the young, charming ... See full summary »
Director: Zdenek Zelenka | Stars: Viktor Preiss, Josef Somr, Petr Kostka, Jan Stastný
Votes: 33
38. Z lékárníkova deníku (1971 TV Movie)
31 min | Comedy, Fantasy
The pharmacist lives a happy but monotonous life. His apartment is above the pharmacy, his wife cooks for him and in the afternoons he works in the pharmacy so that he can devote himself to... See full summary »
Director: Vít Olmer | Stars: Václav Mares, Marie Drahokoupilová, Vít Olmer, Milan Mach
39. Beauty Secrets (2014 Video)
Unrated | 45 min | Sci-Fi
Fifty six year old Amanda Gray was a spokesperson and human Guinea pig for Frank Stein Industries, but how far will they go to cover up a fatally adverse reaction to their body restructuring process.
Director: Nathyn Masters | Stars: Deann Baker, Rich Edward, Tommy Nowicki, Shawn Jolly
Votes: 5
40. Future Medicine & the Curse of Immortality (2017 Video)
7 min | Short, Talk-Show
Dave Cullen discusses the problems that may come with us halting the aging process.
Stars: Dave Cullen, Karl Martin, Arjun Bansal
42. Skrín (2001 TV Movie)
25 min | Comedy, Fantasy, Mystery
Director: Roman Vávra | Stars: Jirí Lábus, Eva Holubová, Oldrich Kaiser, Stella Zázvorková
43. Health Reminder (2007)
4 min | Animation, Short
A black sarcastic look at drugs, the prescription kind, and their over-presence in medical practice The 1st installment of the Health Reminder series.
Director: David Firth | Star: David Firth
Votes: 64
44. The Test (I) (2011)
6 min | Short, Comedy, Fantasy
A man becomes a test subject, and the other men in his drug trial group begin disappearing.
Director: Kevin MacDonald | Stars: Carolyn Bennett, Winston Spear, Scott McCrickard, Mark Andrada
Votes: 31
45. I nyhta tou ptomatos (2005)
11 min | Short, Action, Comedy
A zombie marathon movie night in a mansion turns into the real thing after one guy gets hit by car on his way home and tries to return to the house covered in blood.
Director: Filip Halo | Stars: Mei Papalexiou, Thaleia Kanakari, Thodoris Mihopoulos, Filip Halo
Votes: 13
46.
3rd Rock from the Sun (1996–2001)
Episode:
Sex and the Sally
(1999)
TV-PG | 22 min | Comedy, Family, Sci-Fi
Dick learns about tipping while Sally learns sex can lead to pregnancy.
Director: Terry Hughes | Stars: John Lithgow, Kristen Johnston, French Stewart, Joseph Gordon-Levitt
Votes: 287
47.
The Adventures of Shirley Holmes (1997–2000)
Episode:
The Case of the Singer's Secret
(1997)
Family, Mystery
When tabloid journalists link Robert Holmes with a lovely rock singer who's wanted for murder by the police, Shirley fears the worst. She manages to track the woman to an old fencing studio... See full summary »
Director: Gary Harvey | Stars: Meredith Henderson, John White, Sarah Strange, Chris Humphreys
Votes: 35
48.
Maid Marian and Her Merry Men (1989–1994)
Episode:
The Wise Woman of Worksop
(1994)
24 min | Adventure, Comedy, Family
The gang are suffering from insomnia and keeping everybody else awake so Gladys gives them a cure, Sleepy Cake, though it only succeeds in making them look like the Beatles. Gladys says her... See full summary »
Director: David Bell | Stars: Kate Lonergan, Adam Morris, Danny John-Jules, Howard Lew Lewis
Votes: 19
49.
Max Headroom (1987–1988)
Episode:
Blipverts
(1987)
TV-PG | 60 min | Comedy, Sci-Fi
Top TV reporter Max Edison discovers Network 23 is experimenting with advertising that is lethal to some viewers. His boss tries to kill him and copy his mind to a controllable simulation. Instead Edison survives - and Max Headroom is born.
Director: Farhad Mann | Stars: Matt Frewer, Amanda Pays, George Coe, Chris Young
Votes: 103
50.
Power Rangers DinoThunder (2004)
Episode:
Leader of the Whack
(2004)
TV-Y7-FV | 22 min | Action, Adventure, Family
Trent sets out so that he can't harm anyone when he runs into Cassidy and Devin. A meteor crash lands nearby so they go to investigate and are met by Ethan, Kira, and Conner who are less ... See full summary »
Director: Eamon O'Sullivan | Stars: James Napier Robertson, Kevin Duhaney, Jason David Frank, Emma Lahana
Votes: 74