The heroine of "The She Wolf" walks into "The Last Hope" saloon in "Mad Dog" one night, and discovers the Chinese owner and a crooked sheriff cheating a stranger at a game of cards. Drawing her shooting irons she starts to take a hand in the game herself. During the fighting that follows, the stranger is wounded, and the heroine carries him off to her shack and takes care of him. Several days later, the sheriff, who is the head of a band of outlaws, robs the mail coach and leaves a number of letters scattered on the road. The two-gun young woman picks up one of the letters and learns that it was written by Sallie Bigby to her sweetheart, John Williams. It tells him that Sallie's father is in the power of the Chinese saloon keeper, and that she will be compelled to marry him unless she is rescued. "The She Wolf" goes to the place, starts a lively scrap for the second time, and carries Sallie off to her cabin. Here matters are arranged properly. Sallie and her sweetheart meet and the stranger lets it be known that he intends to make the girl who nursed him back to health his wife.