Paul threatens to shoot a neighbor's champion bull, an often escapee from his quarters, after it almost kills Timmy and then is excused of the demise of the bull actually poisoned by the neighbor's bitter hired man.
Timmy observes what he believes is a wild horse which becomes a menace to the local farms but persuades Paul to convince the local farmers to spare the life of the horse which is later learned to be an escaped thoroughbred.
In Paul's absence, Timmy is unable to shoot a dog strayed on to the Martin farm that has become rabid because he and Lassie have befriended the dog before the dog contracted disease.
Lassie is accidentally ejected from a train baggage car during a trip the Martins are taking to Chicago where Paul is to be the local representative to the national Grange committee.
A trained war mule that Cully has received for a WW1 veterans parade goes berserk after eating dried lead base paint dropped on hay and is threatened with destruction by authorities for being a dangerous animal.
When Timmy learns at a Nike base that the military needs German Shepherds, he rescues an abused dog from the pound to train for military use but the dog's dispirited nature proves an frustrating obstacle.
When Timmy sees a man destroy a eagle egg Timmy replaces the egg with another egg, a goose egg. To Timmy surprise the eagle accept the gosling when the egg hatches.
An impoverished family fleeing a drought stricken farm stay overnight with Martins after Timmy draws them in by a prank but the family's boy runs off into woods during deer season when he hears his dog cannot be kept.
At Paul's offer to pay Cully to use Cully's farm, Cully sees it as criticism of his age and overworks himself to correct the perceived insult until Lassie works with Cully's old dog to show old and young can work for the benefit both.
Ruth acting as a volunteer fire watcher and Timmy are endangered in the watchtower when a carelessly discarded cigarette starts a forest fire and a ranger near the fire has been thrown by his horse frightened by a snake.
An operator of a carnival dog show dog-naps and disguises Lassie for Lassie's ability to learn trick when the health of his main canine performer falters .
A sea captain has brought a male ostrich for a fair sulky race but must prove to the judge that the bird is ready to race a horse and the captain must call on Timmy to drive while Ruth is reluctant due to a nesting female's aggression.
Timmy and Cully search for a gold mine after Lassie find a gold miner's burro which leads to problems for both of them and which Lassie comes to the rescue.
A girl's horse who is past his rodeo glory days is made skittish by an apprehension of Lassie and later that apprehension will prove useful in resurrecting the rodeo career of girl's father returning to the arena after injury.
Lassie finds a doll that could be a clue do the location of a missing six year old city girl at time when a huge aqueduct ditch is about to be filled by a significant amount of water.
Timmy erroneously believes that his operation of a machine he and his friends have made to contact Martians has caused an army plane to crash but the army believes that Lassie's behavior at the time of crash is a clue to accident.
During an awesome vacation at the Grand Canyon, Timmy's mule train descent down the canyon is disrupted by Lassie and later Timmy is helped by a befriended blind man and Lassie when Timmy is stuck on a path off the rim.
Cully inherits a famed tracking bloodhound whose senses Timmy discovers are failing but is loathe to disillusion Cully even when the dog is called to track a hobo thought to steal Ruth's full wallet which has really been pilfered by a crow.
After a police dog and policeman befriended by Timmy and Lassie are shot by a bank robber, the dog on the loose becomes aggressive to the point of attack and might be killed by authorities except the dog is gentled by Timmy and Lassie.
Lassie is unable to follow the rules during a coon competition and, being thought mean, is barred from a swim competition which decision is reversed but Lassie loses because she saves the life of an struggling old dog.
During a dry spell, local farmers set traps to catch animals down from the woods to feed on farm crops which traps Cully springs as dangerous thus the farmers want Cully declared incompetent so Timmy wants Cully to reset the traps.
Timmy begins to feed a doe that has fled a fire in the woods just prior to hunting season and tries to capture the deer against the orders of Paul and Ruth but puts the deer in further danger.
When the fire chief's Dalmatian is killed at a fire, Timmy loans Lassie to the chief for during the day but Lassie becomes enthralled with the fire engine and fire chasing to the extent she ignores Timmy.
Timmy fails to obtain a service dog for a blind boy (Joey) so the boy will make friends and then offers Lassie to the boy but the Martins and the boy's mother introduce Joey to a camp for blind children.
Lassie eschews a kitten given to her by a neighbor to compensate for not having puppies taking instead a mountain lion cub for which the mother comes looking.
A pair of men steal dogs for ransom until they lock up Lassie after stealing Lassie with their vehicle at which time Lassie frees the stolen dogs and alerts the law.
An illegally entered Mexican boy found injured by Timmy places the Martins in legal jeopardy as both Timmy and the Mexican boy struggle with doing the right thing.
When Pearlie Mae Yochim and her son Billy Joe, grieving over the loss of his dog and his father, visit the Martins on Christmas Eve,the boys rescue a man from under a sleigh and then find gifts in the Martin's yard including a puppy.
Cully foists a mischievous escaped parrot on Ruth as an ostensible birthday gift and will not take it back until Cully learns that there is a reward involved.