Lu tries to convince a deaf family to get cochlear implants; Dana treats a heroin-addicted woman who wants to get clean without going through the pain of withdrawal.
Environmental toxins in a low-income housing unit trigger early menopause in one of its 25-year-old residents. A new mother spirals into depression and runs away from home. Dana meets Nick's mother.
Lu treats a 12-year-old girl with gonorrhea who accuses her teacher of giving her the disease; Dana discovers that two of her pregnant patients unknowingly have the same father.
A mother believes that the medication Lu prescribed for her autistic daughter is helping her speak; Dana is torn between a patient's husband and mother about taking the patient off life support.
Dana cares for a priest who has been disguising herself as a man; Lu prescribes a drug for a woman diagnosed with sickle cell anemia whose pharmacist won't carry it for fear of his store being robbed.
Lu treats a woman who goes on a hunger strike in order to make sure her son isn't executed for murder; Dana contemplates her future at Rittenhouse after a pregnant woman loses her baby during childbirth.
Lu and Dana butt heads over a deceased young woman's fertilized eggs; a dying patient of Lu is in need of a heart transplant; Peter's mother pays a visit.
Dr. Jackson finds himself in hot water after denying a job to a overweight woman; Dana treats a patient who is diagnosed with Gulf War Syndrome; Lana cares for an abandoned newborn baby.
Dana treats a former high school rival who is diagnosed with a brain tumor; an ER nurse plans to sue the hospital after contracting HIV from a patient.
As Lu travels to Puerto Rico where her grandmother needs a bone marrow transplant, she flashes back to her days as a resident and how she met Peter and Lana.
Lu helps out a mother who has been diagnosed with Alzheimer's that is in danger of losing custody of her teenage Down Syndrome son; Dana is concerned about the welfare of a pregnant alcoholic woman.
A patient of Dana's ignores her advice when she decides to have her troubled adoptive teenage daughter undergo rebirthing therapy; Lu treats another patient of Dana's who is sick with tuberculosis.
When Dana's patient gives birth to twins, it's revealed that one baby is black and the other is white; Lu suspects that a woman suffering from chronic back pain has an addiction to prescription drugs; Nick treats a young boy with suspicious bruises.
Dana treats a male acquaintance of hers who is diagnosed with cancer; Lu gets in trouble with the police after defending a diabetic woman who was mistaken as being a drunk driver.
Dana treats a promising young figure skater with osteoporosis who is determined to compete in the Olympics; Lu is not thrilled with the father of Marc's new girlfriend.
Lu helps out a woman with carpal tunnel syndrome whose job won't cover her medical condition; Dana treats a pregnant woman and her teenage son for lead poisoning.