Wife, mother, and psychic Allison DuBois (Arquette) can communicate with the dead and is convinced she can use her gift to help solve crimes. She's put to the test when she gets a call from the Texas Rangers.
Allison is partnered with Detective Lee Scanlon on a case involving the strange murders of newlywed couples. Joe tries to plan a surprise party for Allison.
Allison's dream couldn't be more confusing, mimicking the story line of "Little Red Riding Hood": a snarling wolf chases her through a Phoenix airport where she has no choice but to jump from a jetway.
When visiting another psychic, Allison is told that there is a dark cloud over her marriage and this has a snowball effect on Alison both at work and at and home.
Allison believes a supposed Good Samaritan raped and murdered a red-haired college student. Meanwhile, Allison may be pregnant and Ariel may be a math genius.
Allison knows there's more than mere suicide to the story of a girl who jumps off a cliff. Meanwhile, she predicts her husband's co-worker will have a fatal heart attack.
Allison's half-brother Michael returns from duty in Afghanistan with the nickname Lucky. He's deeply troubled, and Allison recognises his binge-drinking as an attempt to mask his 'gift' - Allison insists he be honest with himself.
Nightmares of a cruel ogre haunt Ariel. While Joe is worried about these dreams, Allison believes that Ariel can help a kidnapped girl by decoding her dreams.
Allison's recurring dream of two young boys who are racing a train leads her to Professor Leonard Cardwell whose area of expertise is communication with the afterlife.
Allison is sick. The medicine she takes makes her have strange dreams - stranger than usual dreams. She dreams she is involved in a very old TV show called I Married A Mind Reader. She's not sure the real life murderer is the right person.
Allison has a dream about a pilot who saves a plane from crashing. Later she finds out that the pilot is suspected of a murder and she gets confused about what her dream means with regard to the murder.
Things go from bad to worse when Allison's mother-in-law comes to visit. A once-closed case is re-opened to try to find out if the convicted person is actually innocent.
Allison encounters a psychopathic doctor who raped and murdered numerous teenage girls years ago. After learning that an evil soul has been possessing people, she sets forth to stop it before a new victim is found.
After seeing Capt. Kenneth Push in a vision at a murder scene, Allison calls upon his assistance to find a serial killer. However, the only way Capt. Push can help is by literally putting his life on the line.
A song that keeps repeating in Allison's head leads her to a clue about a missing coed, but she runs up against the church and the sanctity of the confessional and is afraid they won't find the girl in time.
Allison's sleepwalking puts her physically at risk, and her dreams put the family financially at risk. Meanwhile, there's a missing boy to find and a kidnapper to catch.
Allison's vision of a murder could potentially derail Devalos' reelection campaign, and when Devalos keeps getting upstaged in court, it's up to Allison to find out the truth.
Joe serves his jury duty on a case against a man accused of murdering his rich wife. Allison starts having visions about the man but D.A. Devalos orders her not to work on the case because of a conflict of interests.
Allison thinks that there is another dimension in art. While at an art exhibit she see three-dimensional images pop out. These all help lead her to uncover a deadly secret.
Allison dreams about hitting a girl with her car and a woman whose house is haunted. She finds out that the woman killed herself. Now Allison is trying to put all the pieces together.