When Freddie Pink, William's childhood friend, calls on Murdoch to solve a crime, she becomes his chief suspect. It takes the brilliance of both detectives to get at the truth.
Detective Murdoch and Dr. Ogden investigate the poisoning of a philandering businessman; Dr. Rebecca James has suspicions about a fellow medical student's suicide.
A murderer claims to be possessed by the spirit of Murdoch's arch-nemesis, James Gillies. Murdoch and Ogden begin to suspect that Gillies may still be alive.
Murdoch devises a mysterious tonic that he claims is the fountain of youth, and has worked on the Inspector, but his pursuit of a commercial partnership alarms Crabtree.
The discovery of a young girl's body and some grotesque sketches leads Murdoch to suspect a group of teenagers obsessed with death and the macabre, which includes a young H.P. Lovecraft.
Murdoch's investigation into the death of a roller-skating champion takes him into the world of an aggressive and ruthless sporting competition. Rebecca James competes in a roller-skating race, but her competitors have an unknown advantage.