With the gang disbanded, and Crystal Cove being tormented by an evil man-baby named "Crybaby Clown," the new Mayor decides it's time to bring Mystery Incorporated back together.
Velma and Hot Dog Water (as the new Daphne) work for Mr. E to retrieve a museum exhibit from Moscow, but the exhibit - a witch and her house - comes to life and torments Crystal Cove.
Crybaby Clown is back with a vengeance, kidnapping the citizens of Crystal Cove. When he nabs Daphne, however, the gang wastes no time in solving the mystery.
As the gang sets out to solve the mystery of the Dreamweaver, who is causing citizens to destroy the things they love the most, Fred gets a visit from his real parents.
The gang pursue the Hodag of Horror, a beast from a mobile museum that mysteriously stops in Crystal Cove, while Professor Pericles reunites the original Mystery Incorporated.
The art world comes to Crystal Cove in a mystery driven by a work of art that tries to destroy its creator. With Scooby in an emo band, things get pretty heavy!
After the gang is attacked by the Graveyard Ghoul, they try not to commit "villain profiling," even when the perfect suspect is right before their eyes.
The Mystery Inc. gang climb Mount Diabla to solve the mystery of a dark winged angel of destruction and a mysterious Spanish Galleon that once belonged to the conquistadors who founded Crystal Cove.
When a crazed ghostly Puritan judge named Hebediah Grimm starts terrorizing the youth of Crystal Cove on Lovers' Lane, the Mystery Inc. gang get involved.
When Cassidy is attacked by deep-sea robots, the gang decides to help her unravel the mystery of who is sending them and why. This is going to call for a little deep-sea adventure.
Dynomutt and Blue Falcon team up with the Mystery Inc. gang to solve the mystery of a horrible dragon-man-robot hybrid that's terrorizing Crystal Cove.
The Mystery Inc. gang investigate the Sheriff's claims of aliens in Crystal Cove who are pilfering all the town's high-tech devices for their spaceship repairs.
Professor Pericles, desperate for the Planispheric Disk and revenge on Mystery Inc., creates a herd of mutated skull cattle to destroy Crystal Cove and stop them once and for all.
When a motorcycle-riding robber known as the Dandy Highwayman kidnaps all the women of Crystal Cove (including Daphne), it's up to our heroes to put a stop to his rogue ways.
The Mystery Inc. gang heads south of the border to search ancient Mayan ruins for the burial chamber of the Hunters of Secrets and the Heart of the Jaguar.
The gang returns from their trip, and find that the whole town has been enslaved by Professor Pericles, Mr. E, Brad, and Judy. So the gang has to save the town, by causing an uprising.