Among those looking for love are self-confessed romantic Becky, chef Luke from Hull, who has Tourette's syndrome and bookseller Sam, from Cambridgeshire who has Asperger's syndrome.
Trainee accountant and Bollywood fanatic Nisar has a stammer and wants to face his fear of talking to women. Art student Daniel has Asperger's. Fashionista Fatima has achondroplasia, a form of dwarfism.
Having learned to walk and talk again following a major stroke 8 years ago, Amber is ready to meet her Prince Charming. Nick uses music to overcome his learning disability. Richard is fanatical about trains.
Car enthusiast Alex is autistic. Identical twin Jason has Asperger's and tends to rush into things. Male model Tom has been the subject of much tweeting since his last appearance on the show.
Film fan Charlotte from Lincolnshire has Asperger's and is a sucker for romance. Mitch from Southampton was born deaf and relies on lip reading. James from Hampshire has Down's Syndrome and is looking for that special lady.
Dating newbie Rory from Coventry hopes to meet a girl who shares his love of horror films. Roland wants a leading lady to serenade. Animal lover Molly wants someone to cuddle other than her cat.
This week's singletons looking for love are personal trainer Jordan, who suffers from speech problems; vlogger Paige, who has cerebral palsy; and basketball player Sam from Shropshire.
The cameras catch-up with charity worker Ray, who's celebrates his first anniversary with Christine. And plane spotter Jason and Luke from Hull resume their search for The One.
It's almost Christmas and some familiar faces from the show have made some big plans. Lizzie and Joseph host their first festive party as a couple and Daniel has a special wish that only his girlfriend Lily can make come true.