As Violet runs for election as a councillor, Lucille befriends an elderly woman facing eviction, and Sister Hilda supports a Ghanaian family suffering from a mysterious illness.
A troubled mother receives support from Shelagh and an unexpected source, Valerie helps a woman whose child is born with a cleft palate, and Phyllis has ambitious plans for the Whitsun bank holiday.
A young bride-to-be suffers an identity crisis after the diagnosis of a hidden condition, an expectant father is diagnosed with a rare condition himself, and romance is in the air for Lucille.
When Phyllis is admitted to hospital, Mother Mildred returns to cover her assignments, and soon causes a stir, while Lucille cares for an unwed teenager who wants to keep her baby.
A woman's pregnancy is affected by her husband's infidelity, Sister Frances faces her first solo delivery, Shelagh receives news about May, and Valerie's loyalty is tested.
As Shelagh plans a ball to raise money for new medical equipment, Valerie must come to terms with recent events, while Sister Hilda assists a terminally ill young woman.