Sister Julienne intervenes in the case of a pregnant prostitute, a family's plan to leave Poplar are up in the air when a mysterious illness strikes, and Sgt. Woolf faces a health crisis of his own.
Lucille encounters a defiant expectant mother who is less than kind, Phyllis attempts to help an immigrant mother with an alarming medical condition, and Shelagh and Trixie put on a fashion show to raise funds for the maternity home.
Nonnatus House welcomes four male junior doctors to live and work among the midwives while Fred tries to help a sick man whose home is to be demolished.
Trixie helps a blind mother care for her new baby, Kevin makes an error which troubles Sister Frances, and Valerie becomes concerned for her grandmother.
The local council threatens to cut funding to Nonnatus House, which may face demolition. Two pregnant women discover they have something surprising in common.
Sister Monica Joan is rushed to hospital, while Trixie is less than impressed to receive a subscription to a Marriage Bureau as a Christmas present. Meanwhile, the circus is in town.