Sort by Popularity - Most Popular Movies and TV Shows tagged with keyword "experiment-gone-wrong"
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1. Once Upon a Time (2011–2018)
TV-PG | 60 min | Adventure, Fantasy, Romance
A young woman with a troubled past is drawn to a small town in Maine where fairy tales are to be believed.
Stars: Ginnifer Goodwin, Jennifer Morrison, Lana Parrilla, Robert Carlyle
Votes: 237,297
2. Jurassic World Dominion (2022)
PG-13 | 147 min | Action, Adventure, Sci-Fi
Four years after the destruction of Isla Nublar, Biosyn operatives attempt to track down Maisie Lockwood, while Dr Ellie Sattler investigates a genetically engineered swarm of giant insects.
Director: Colin Trevorrow | Stars: Chris Pratt, Bryce Dallas Howard, Laura Dern, Sam Neill
Votes: 206,170 | Gross: $376.85M
3. Jurassic Park (1993)
PG-13 | 127 min | Action, Adventure, Sci-Fi
A pragmatic paleontologist touring an almost complete theme park on an island in Central America is tasked with protecting a couple of kids after a power failure causes the park's cloned dinosaurs to run loose.
Director: Steven Spielberg | Stars: Sam Neill, Laura Dern, Jeff Goldblum, Richard Attenborough
Votes: 1,069,004 | Gross: $402.45M
4. Logan (2017)
R | 137 min | Action, Drama, Sci-Fi
In a future where mutants are nearly extinct, an elderly and weary Logan leads a quiet life. But when Laura, a mutant child pursued by scientists, comes to him for help, he must get her to safety.
Director: James Mangold | Stars: Hugh Jackman, Patrick Stewart, Dafne Keen, Boyd Holbrook
Votes: 833,125 | Gross: $226.28M
5. Eternal Sunshine of the Spotless Mind (2004)
R | 108 min | Drama, Romance, Sci-Fi
When their relationship turns sour, a couple undergoes a medical procedure to have each other erased from their memories forever.
Director: Michel Gondry | Stars: Jim Carrey, Kate Winslet, Tom Wilkinson, Gerry Robert Byrne
Votes: 1,079,706 | Gross: $34.40M
6. Spider-Man (2002)
PG-13 | 121 min | Action, Adventure, Sci-Fi
After being bitten by a genetically-modified spider, a shy teenager gains spider-like abilities that he uses to fight injustice as a masked superhero and face a vengeful enemy.
Director: Sam Raimi | Stars: Tobey Maguire, Kirsten Dunst, Willem Dafoe, James Franco
Votes: 881,334 | Gross: $403.71M
7. Weird Science (1985)
PG-13 | 94 min | Comedy, Romance, Sci-Fi
Two high-school nerds use a computer program to literally create the perfect woman, who promptly turns their lives upside-down.
Director: John Hughes | Stars: Anthony Michael Hall, Ilan Mitchell-Smith, Kelly LeBrock, Bill Paxton
Votes: 97,572 | Gross: $23.83M
8. The Guest (I) (2014)
R | 100 min | Action, Mystery, Thriller
A soldier introduces himself to the Peterson family, claiming to be a friend of their son who died in action. After the young man is welcomed into their home, a series of accidental deaths seem to be connected to his presence.
Director: Adam Wingard | Stars: Dan Stevens, Sheila Kelley, Maika Monroe, Joel David Moore
Votes: 107,131 | Gross: $0.32M
9. Jurassic World (2015)
PG-13 | 124 min | Action, Adventure, Sci-Fi
A new theme park, built on the original site of Jurassic Park, creates a genetically modified hybrid dinosaur, the Indominus Rex, which escapes containment and goes on a killing spree.
Director: Colin Trevorrow | Stars: Chris Pratt, Bryce Dallas Howard, Ty Simpkins, Judy Greer
Votes: 680,233 | Gross: $652.27M
10. The Mist (2007)
R | 126 min | Horror, Sci-Fi, Thriller
A freak storm unleashes a species of bloodthirsty creatures on a small town, where a small band of citizens hole up in a supermarket and fight for their lives.
Director: Frank Darabont | Stars: Thomas Jane, Marcia Gay Harden, Laurie Holden, Andre Braugher
Votes: 341,090 | Gross: $25.59M
11. Iron Man Three (2013)
PG-13 | 130 min | Action, Adventure, Sci-Fi
When Tony Stark's world is torn apart by a formidable terrorist called the Mandarin, he starts an odyssey of rebuilding and retribution.
Director: Shane Black | Stars: Robert Downey Jr., Guy Pearce, Gwyneth Paltrow, Don Cheadle
Votes: 900,381 | Gross: $409.01M
12. The Stand (1994)
Not Rated | 90 min | Adventure, Drama, Fantasy
After a deadly plague kills most of the world's population, the remaining survivors split into two groups - one led by a benevolent elder and the other by a malevolent being - to face each other in a final battle between good and evil.
Stars: Gary Sinise, Molly Ringwald, Jamey Sheridan, Laura San Giacomo
Votes: 38,471
13. Snowpiercer (2013)
R | 126 min | Action, Drama, Sci-Fi
In a future where a failed climate change experiment has killed all life except for the survivors who boarded the Snowpiercer (a train that travels around the globe), a new class system emerges.
Director: Bong Joon Ho | Stars: Chris Evans, Jamie Bell, Tilda Swinton, Ed Harris
Votes: 389,532 | Gross: $4.56M
14. The Incredible Hulk (2008)
PG-13 | 112 min | Action, Adventure, Sci-Fi
Bruce Banner, a scientist on the run from the U.S. Government, must find a cure for the monster he turns into whenever he loses his temper.
Director: Louis Leterrier | Stars: Edward Norton, Liv Tyler, Tim Roth, William Hurt
Votes: 524,100 | Gross: $134.52M
15. Venom (2018)
PG-13 | 112 min | Action, Adventure, Sci-Fi
A failed reporter is bonded to an alien entity, one of many symbiotes who have invaded Earth. But the being takes a liking to Earth and decides to protect it.
Director: Ruben Fleischer | Stars: Tom Hardy, Michelle Williams, Riz Ahmed, Scott Haze
Votes: 539,327 | Gross: $213.52M
16. Quantum Leap (1989–1993)
TV-PG | 60 min | Action, Adventure, Drama
During an experiment into time travel, a scientist finds himself trapped in the past, "leaping" into the lives of different people, sorting out their problems and changing history in hopes of getting back to his own life in the present.
Stars: Scott Bakula, Dean Stockwell, Deborah Pratt, Dennis Wolfberg
Votes: 36,532
17. Captain Marvel (2019)
PG-13 | 123 min | Action, Adventure, Sci-Fi
Carol Danvers becomes one of the universe's most powerful heroes when Earth is caught in the middle of a galactic war between two alien races.
Directors: Anna Boden, Ryan Fleck | Stars: Brie Larson, Samuel L. Jackson, Ben Mendelsohn, Jude Law
Votes: 611,797 | Gross: $426.83M
18. Fantastic Four (2015)
PG-13 | 100 min | Action, Adventure, Sci-Fi
Four young outsiders teleport to an alternate and dangerous universe which alters their physical form in shocking ways. The four must learn to harness their new abilities and work together to save Earth from a former friend turned enemy.
Director: Josh Trank | Stars: Miles Teller, Kate Mara, Michael B. Jordan, Jamie Bell
Votes: 176,753 | Gross: $56.12M
19. Species (1995)
R | 108 min | Action, Horror, Sci-Fi
A group of scientists try to track down and trap a killer alien seductress before she successfully mates with a human.
Director: Roger Donaldson | Stars: Natasha Henstridge, Michael Madsen, Ben Kingsley, Alfred Molina
Votes: 85,369 | Gross: $60.07M
20. Hulk (2003)
PG-13 | 138 min | Action, Sci-Fi
Bruce Banner, a genetics researcher with a tragic past, suffers an accident that causes him to transform into a raging green monster when he gets angry.
Director: Ang Lee | Stars: Eric Bana, Jennifer Connelly, Sam Elliott, Josh Lucas
Votes: 278,818 | Gross: $132.18M
21. Back to the Future Part II (1989)
PG | 108 min | Adventure, Comedy, Sci-Fi
After visiting 2015, Marty McFly must repeat his visit to 1955 to prevent disastrous changes to 1985...without interfering with his first trip.
Director: Robert Zemeckis | Stars: Michael J. Fox, Christopher Lloyd, Lea Thompson, Tom Wilson
Votes: 573,443 | Gross: $118.50M
22. Ad Astra (2019)
PG-13 | 123 min | Adventure, Drama, Mystery
Astronaut Roy McBride undertakes a mission across an unforgiving solar system to uncover the truth about his missing father and his doomed expedition that now, 30 years later, threatens the universe.
Director: James Gray | Stars: Brad Pitt, Tommy Lee Jones, Ruth Negga, Donald Sutherland
Votes: 260,832 | Gross: $50.19M
23. Resident Evil: Welcome to Raccoon City (2021)
R | 107 min | Action, Horror, Sci-Fi
Set in 1998, this origin story explores the secrets of the mysterious Spencer Mansion and the ill-fated Raccoon City.
Director: Johannes Roberts | Stars: Kaya Scodelario, Robbie Amell, Hannah John-Kamen, Tom Hopper
Votes: 64,288 | Gross: $17.00M
24. Morbius (2022)
PG-13 | 104 min | Action, Adventure, Horror
Biochemist Michael Morbius tries to cure himself of a rare blood disease, but he inadvertently infects himself with a form of vampirism instead.
Director: Daniel Espinosa | Stars: Jared Leto, Matt Smith, Adria Arjona, Jared Harris
Votes: 153,789 | Gross: $73.87M
25. The Nutty Professor (1996)
PG-13 | 95 min | Comedy, Romance, Sci-Fi
Grossly overweight yet good-hearted professor Sherman Klump takes a special chemical that turns him into the slim but obnoxious Buddy Love.
Director: Tom Shadyac | Stars: Eddie Murphy, Jada Pinkett Smith, James Coburn, Larry Miller
Votes: 123,823 | Gross: $128.81M
26. Deep Blue Sea (1999)
R | 105 min | Action, Adventure, Sci-Fi
Searching for a cure to Alzheimer's disease, a group of scientists on an isolated research facility become the prey, as a trio of intelligent sharks fight back.
Director: Renny Harlin | Stars: Thomas Jane, Saffron Burrows, Samuel L. Jackson, Jacqueline McKenzie
Votes: 142,694 | Gross: $73.65M
27. Boss Level (2020)
TV-MA | 100 min | Action, Adventure, Comedy
Trapped in a time loop that constantly repeats the day of his murder, a former special forces agent must unlock the mystery behind his untimely demise.
Director: Joe Carnahan | Stars: Frank Grillo, Mel Gibson, Naomi Watts, Michelle Yeoh
Votes: 79,377
28. Ghost in the Shell (2017)
PG-13 | 107 min | Action, Crime, Drama
In the near future, Major Mira Killian is the first of her kind: A human saved from a terrible crash, who is cyber-enhanced to be a perfect soldier devoted to stopping the world's most dangerous criminals.
Director: Rupert Sanders | Stars: Scarlett Johansson, Pilou Asbæk, Takeshi Kitano, Juliette Binoche
Votes: 228,136 | Gross: $40.56M
29. Monsters vs. Aliens (2009)
PG | 94 min | Animation, Action, Adventure
A woman transformed into a giant after she is struck by a meteorite on her wedding day becomes part of a team of monsters sent in by the U.S. government to defeat an alien mastermind trying to take over Earth.
Directors: Rob Letterman, Conrad Vernon | Stars: Reese Witherspoon, Rainn Wilson, Stephen Colbert, Seth Rogen
Votes: 176,350 | Gross: $198.35M
30. Sliders (1995–2000)
TV-PG | 60 min | Adventure, Fantasy, Sci-Fi
A boy genius and his comrades travel to different parallel universes, trying to find their way back home.
Stars: Jerry O'Connell, Sabrina Lloyd, John Rhys-Davies, Cleavant Derricks
Votes: 20,424
31. Ant-Man and the Wasp (2018)
PG-13 | 118 min | Action, Adventure, Comedy
As Scott Lang balances being both a superhero and a father, Hope van Dyne and Dr. Hank Pym present an urgent new mission that finds the Ant-Man fighting alongside The Wasp to uncover secrets from their past.
Director: Peyton Reed | Stars: Paul Rudd, Evangeline Lilly, Michael Peña, Walton Goggins
Votes: 450,654 | Gross: $216.65M
32. Dark Angel (2000–2002)
TV-14 | 60 min | Action, Drama, Mystery
A group of genetically-enhanced children escape from a lab project. Years later we meet Max, one of the escapees who now works for a messenger service in the post-apocalyptic Pacific Northwest.
Stars: Jessica Alba, Michael Weatherly, Richard Gunn, J.C. MacKenzie
Votes: 34,637
33. Lights Out (II) (2016)
PG-13 | 81 min | Horror, Mystery
Rebecca must unlock the terror behind her little brother's experiences that once tested her sanity, bringing her face to face with a supernatural spirit attached to their mother.
Director: David F. Sandberg | Stars: Teresa Palmer, Gabriel Bateman, Maria Bello, Billy Burke
Votes: 142,551 | Gross: $67.27M
34. Splice (2009)
R | 104 min | Horror, Sci-Fi
Genetic engineers Clive Nicoli and Elsa Kast hope to achieve fame by successfully splicing together the DNA of different animals to create new hybrid animals for medical use.
Director: Vincenzo Natali | Stars: Adrien Brody, Sarah Polley, Delphine Chanéac, Brandon McGibbon
Votes: 101,848 | Gross: $17.00M
35. The Blob (1988)
R | 95 min | Horror, Sci-Fi, Thriller
A deadly entity from space crash-lands near a small town and begins consuming everyone in its path. Panic ensues as shady government scientists try to contain the horrific creature.
Director: Chuck Russell | Stars: Shawnee Smith, Kevin Dillon, Donovan Leitch Jr., Jeffrey DeMunn
Votes: 43,607 | Gross: $8.25M
36. The Incredible Hulk (1978–1982)
TV-PG | 60 min | Action, Adventure, Drama
A fugitive scientist has the curse of becoming a powerful green monster under extreme emotional stress.
Stars: Bill Bixby, Lou Ferrigno, Jack Colvin, Charles Napier
Votes: 16,168
37. Leviathan (1989)
R | 98 min | Adventure, Horror, Mystery
Perched on the hull of a wrecked Soviet freighter, a team of deep-sea miners led by head oceanographer Steven Beck comes face to face with a mutant creature that's the product of a failed genetic experiment.
Director: George P. Cosmatos | Stars: Peter Weller, Richard Crenna, Amanda Pays, Daniel Stern
Votes: 23,853 | Gross: $15.70M
38. Morgan (2016)
R | 92 min | Action, Horror, Sci-Fi
A corporate risk-management consultant must decide whether or not to terminate an artificially created humanoid being.
Director: Luke Scott | Stars: Kate Mara, Anya Taylor-Joy, Rose Leslie, Michael Yare
Votes: 46,155 | Gross: $3.91M
39. The Cloverfield Paradox (2018)
PG-13 | 102 min | Action, Horror, Sci-Fi
Orbiting a planet on the brink of war, scientists test a device to solve an energy crisis, and end up face-to-face with a dark alternate reality.
Director: Julius Onah | Stars: Gugu Mbatha-Raw, David Oyelowo, Daniel Brühl, John Ortiz
Votes: 113,154
40. Primer (2004)
PG-13 | 77 min | Drama, Sci-Fi, Thriller
Four friends/fledgling entrepreneurs, knowing that there's something bigger and more innovative than the different error-checking devices they've built, wrestle over their new invention.
Director: Shane Carruth | Stars: Shane Carruth, David Sullivan, Casey Gooden, Anand Upadhyaya
Votes: 114,300 | Gross: $0.42M
41. Flatliners (1990)
R | 115 min | Drama, Horror, Sci-Fi
Five medical students experiment with "near death" experiences, until the dark consequences of past tragedies begin to jeopardize their lives.
Director: Joel Schumacher | Stars: Kiefer Sutherland, Kevin Bacon, Julia Roberts, William Baldwin
Votes: 93,565 | Gross: $61.49M
42. Frankenstein (1931)
Passed | 70 min | Drama, Horror, Sci-Fi
Dr Henry Frankenstein is obsessed with assembling a living being from parts of several exhumed corpses.
Director: James Whale | Stars: Colin Clive, Mae Clarke, Boris Karloff, John Boles
Votes: 79,848
43. Victor Frankenstein (2015)
PG-13 | 110 min | Drama, Horror, Sci-Fi
Told from Igor's perspective, we see the troubled young assistant's dark origins, his redemptive friendship with the young medical student Viktor Von Frankenstein, and become eyewitnesses to the emergence of how Frankenstein became the man - and the legend - we know today.
Director: Paul McGuigan | Stars: Daniel Radcliffe, James McAvoy, Jessica Brown Findlay, Andrew Scott
Votes: 60,340 | Gross: $5.78M
44. Mary and the Witch's Flower (2017)
PG | 103 min | Animation, Adventure, Family
Based on "The Little Broomstick" by Mary Stewart, a strange flower grants a girl magic powers.
Director: Hiromasa Yonebayashi | Stars: Hana Sugisaki, Ryunosuke Kamiki, Yûki Amami, Fumiyo Kohinata
Votes: 16,353 | Gross: $2.42M
45. House on Haunted Hill (1999)
R | 93 min | Horror, Mystery, Thriller
An amusement park mogul offers a group of diverse people $1,000,000 to spend the night in a haunted house with a horrifying past.
Director: William Malone | Stars: Geoffrey Rush, Famke Janssen, Taye Diggs, Peter Gallagher
Votes: 60,180 | Gross: $40.85M
46. Push (2009)
PG-13 | 111 min | Action, Sci-Fi, Thriller
Two young Americans with special abilities must race to find a girl in Hong Kong before a shadowy government organization called Division does.
Director: Paul McGuigan | Stars: Camilla Belle, Dakota Fanning, Chris Evans, Colin Ford
Votes: 115,641 | Gross: $31.81M
47. Hardcore Henry (2015)
R | 96 min | Action, Adventure, Sci-Fi
Henry is resurrected from death with no memory, and he must save his wife from a telekinetic warlord with a plan to bio-engineer soldiers.
Director: Ilya Naishuller | Stars: Sharlto Copley, Tim Roth, Haley Bennett, Danila Kozlovskiy
Votes: 102,033 | Gross: $9.25M
48. The Lawnmower Man (1992)
R | 108 min | Horror, Sci-Fi
A simple man is turned into a genius through the application of computer science.
Director: Brett Leonard | Stars: Jeff Fahey, Pierce Brosnan, Jenny Wright, Mark Bringelson
Votes: 39,091 | Gross: $32.10M
49. Southland Tales (2006)
R | 145 min | Comedy, Drama, Mystery
During a three-day heat wave just before a huge 4th of July celebration, an action star stricken with amnesia meets up with a porn star who is developing her own reality TV project, and a policeman who holds the key to a vast conspiracy.
Director: Richard Kelly | Stars: Dwayne Johnson, Sarah Michelle Gellar, Seann William Scott, Carlos Amezcua
Votes: 40,666 | Gross: $0.28M
50. Re-Animator (1985)
Unrated | 84 min | Comedy, Horror, Sci-Fi
After an odd new medical student arrives on campus, a dedicated local and his girlfriend become involved in bizarre experiments centering around the re-animation of dead tissue.
Director: Stuart Gordon | Stars: Jeffrey Combs, Bruce Abbott, Barbara Crampton, David Gale
Votes: 71,607 | Gross: $2.02M