Sort by Popularity - Most Popular Movies and TV Shows With Seth MacFarlane

1. Bones (2005–2017)

TV-14 | 40 min | Crime, Drama, Mystery

F.B.I. Special Agent Seeley Booth teams up with the Jeffersonian's top anthropologist, Dr. Temperance Brennan, to investigate cases where all that's left of the victims are their bones.

Stars: Emily Deschanel, David Boreanaz, Michaela Conlin, T.J. Thyne

Votes: 176,590

2. Family Guy (1999– )

TV-MA | 22 min | Animation, Comedy

In a wacky Rhode Island town, a dysfunctional family strives to cope with everyday life as they are thrown from one crazy scenario to another.

Stars: Alex Borstein, Seth MacFarlane, Seth Green, Mila Kunis

Votes: 364,859

3. The Simpsons (1989– )

TV-14 | 22 min | Animation, Comedy

The satiric adventures of a working-class family in the misfit city of Springfield.

Stars: Dan Castellaneta, Nancy Cartwright, Harry Shearer, Julie Kavner

Votes: 436,624

4. Gilmore Girls (2000–2007)

TV-PG | 44 min | Comedy, Drama

A dramedy centering around the relationship between a thirtysomething single mother and her teen daughter living in Stars Hollow, Connecticut.

Stars: Lauren Graham, Alexis Bledel, Keiko Agena, Scott Patterson

Votes: 148,487

5. The Orville (2017–2022)

TV-14 | 44 min | Adventure, Comedy, Drama

Set 400 years in the future, the crew of the U.S.S. Orville continue their mission of exploration, navigating both the mysteries of the universe, and the complexities of their own interpersonal relationships.

Stars: Seth MacFarlane, Adrianne Palicki, Penny Johnson Jerald, Scott Grimes

Votes: 99,970

6. Saturday Night Live (1975– )

TV-14 | 90 min | Comedy, Music

A famous guest host stars in parodies and sketches created by the cast of this witty show.

Stars: The Saturday Night Live Band, Don Pardo, Darrell Hammond, Kenan Thompson

Votes: 52,816

7. Futurama (1999– )

TV-14 | 22 min | Animation, Adventure, Comedy

Philip J. Fry, a pizza delivery boy, is accidentally frozen in 1999 and thawed out on New Year's Eve 2999.

Stars: Billy West, John DiMaggio, Katey Sagal, Tress MacNeille

Votes: 261,361

8. Ted (2024)

TV-MA | Comedy

It's 1993, and Ted the bear's moment of fame has passed. He's living back home with his best friend, John Bennett, and his family. While Ted may be a lousy influence on John, he's a loyal pal who will go out on a limb for friendship.

Stars: Seth MacFarlane, Max Burkholder, Alanna Ubach, Scott Grimes

Votes: 27,456

9. American Dad! (2005– )

TV-MA | 22 min | Animation, Comedy

The escapades of Stan Smith, a conservative C.I.A. Agent dealing with family life, and keeping America safe.

Stars: Seth MacFarlane, Wendy Schaal, Scott Grimes, Rachael MacFarlane

Votes: 136,478

10. Star Trek: Enterprise (2001–2005)

TV-PG | 60 min | Action, Adventure, Drama

A century before Captain Kirk's five-year mission, Jonathan Archer captains the United Earth ship Enterprise during the early years of Starfleet, leading up to the Earth-Romulan War and the formation of the Federation.

Stars: Scott Bakula, John Billingsley, Jolene Blalock, Dominic Keating

Votes: 59,209

11. Will & Grace (1998–2020)

TV-PG | 22 min | Comedy, Romance

Gay lawyer Will and straight interior designer Grace share a New York City apartment. Their best friends are gleeful and proud gay Jack and charismatic, filthy-rich, amoral socialite Karen.

Stars: Eric McCormack, Debra Messing, Megan Mullally, Sean Hayes

Votes: 60,391

12. Sing (2016)

PG | 108 min | Animation, Comedy, Family

In a city of humanoid animals, a hustling theater impresario's attempt to save his theater with a singing competition becomes grander than he anticipates even as its finalists find that their lives will never be the same.

Directors: Garth Jennings, Christophe Lourdelet | Stars: Matthew McConaughey, Reese Witherspoon, Seth MacFarlane, Scarlett Johansson

Votes: 191,649 | Gross: $270.40M

13. Hellboy II: The Golden Army (2008)

PG-13 | 120 min | Action, Adventure, Fantasy

A prince of the mythical world starts a rebellion against humanity in order to rule the Earth. Hellboy and his team must fight to stop him from locating the all-powerful Golden Army.

Director: Guillermo del Toro | Stars: Ron Perlman, Selma Blair, Doug Jones, John Alexander

Votes: 286,307 | Gross: $75.75M

14. Good Times (2024– )

TV-MA | 25 min | Animation, Comedy

The Evans family must manage the challenges of contemporary life, like social issues.

Stars: Jay Pharoah, Marsai Martin, Gerald 'Slink' Johnson, Yvette Nicole Brown

Votes: 818

15. Phineas and Ferb (2007–2024)

TV-G | 15 min | Animation, Short, Action

Phineas and Ferb invent, scheme, and stay one step ahead of their bratty sister. Meanwhile, their pet platypus plots against evil Dr. Doofenshmirtz.

Stars: Vincent Martella, Dan Povenmire, Ashley Tisdale, Jeff 'Swampy' Marsh

Votes: 57,014

16. Ted (2012)

R | 106 min | Comedy

John Bennett, a man whose childhood wish of bringing his teddy bear to life came true, now must decide between keeping the relationship with the bear, Ted or his girlfriend, Lori.

Director: Seth MacFarlane | Stars: Mark Wahlberg, Mila Kunis, Seth MacFarlane, Joel McHale

Votes: 658,453 | Gross: $218.82M

17. Comedy Central Roasts (2003– )

Comedy

Celebrities and comedians belt out good-natured insult comedy jokes at the expense of a guest of honour. The event is hosted by a Roast Master who also takes a jab at the attendees.

Stars: Jeffrey Ross, Yuval David, Greg Giraldo, Lisa Lampanelli

Votes: 193

18. Movie 43 (2013)

R | 94 min | Comedy

A series of interconnected short films follows a washed-up producer as he pitches insane story lines featuring some of the biggest stars in Hollywood.

Directors: Elizabeth Banks, Steven Brill, Steve Carr, Rusty Cundieff, James Duffy, Griffin Dunne, Peter Farrelly, Patrik Forsberg, Will Graham, James Gunn, Brett Ratner, Jonathan van Tulleken, Bob Odenkirk | Stars: Emma Stone, Stephen Merchant, Richard Gere, Liev Schreiber

Votes: 112,429 | Gross: $8.83M

19. The Naked Gun (2025)

Action, Comedy | Pre-production

Based off the widely popular comedy franchise The Naked Gun and television series "Police Squad!" by Jim Abrahams and David Zucker and Jerry Zucker.

Director: Akiva Schaffer | Stars: Kevin Durand, Liam Neeson, Paul Walter Hauser, Pamela Anderson

20. Ted 2 (2015)

R | 115 min | Comedy

Newlywed couple Ted and Tami-Lynn want to have a baby, but in order to qualify to be a parent, Ted will have to prove he's a person in a court of law.

Director: Seth MacFarlane | Stars: Mark Wahlberg, Seth MacFarlane, Amanda Seyfried, Jessica Barth

Votes: 234,264 | Gross: $81.48M

21. Robot Chicken (2001–2022)

TV-MA | 11 min | Animation, Short, Adventure

Pop culture references fly thick and fast as stop-motion animation is featured in sketches lampooning everything from television movies to comic books.

Stars: Seth Green, Matthew Senreich, Breckin Meyer, Tom Root

Votes: 46,308

22. Logan Lucky (2017)

PG-13 | 118 min | Action, Comedy, Crime

Two brothers attempt to pull off a heist during a NASCAR race in North Carolina.

Director: Steven Soderbergh | Stars: Channing Tatum, Adam Driver, Daniel Craig, Farrah Mackenzie

Votes: 162,348 | Gross: $27.78M

23. A Million Ways to Die in the West (2014)

R | 116 min | Comedy, Western

As a cowardly farmer begins to fall for the mysterious new woman in town, he must put his newly found courage to the test when her husband, a notorious gun-slinger, announces his arrival.

Director: Seth MacFarlane | Stars: Seth MacFarlane, Charlize Theron, Liam Neeson, Amanda Seyfried

Votes: 198,724 | Gross: $43.14M

24. Cosmos: A Spacetime Odyssey (2014)

TV-PG | 43 min | Documentary

An exploration of our discovery of the laws of nature and coordinates in space and time.

Stars: Neil deGrasse Tyson, Christopher Emerson, Keythe Farley, Piotr Michael

Votes: 129,039

25. Aqua Teen Hunger Force (2000–2023)

TV-MA | 15 min | Animation, Comedy

The misadventures of a milkshake, an order of fries, a meatball, and their retired next door neighbor in the suburbs of New Jersey.

Stars: Dave Willis, Carey Means, Dana Snyder, Matt Maiellaro

Votes: 26,839

26. The Daily Show (1996– )

TV-14 | 22 min | Comedy, News, Talk-Show

A comedy news show featuring humorous takes on top stories.

Stars: Jon Stewart, Trevor Noah, Stephen Colbert, Roy Wood Jr.

Votes: 48,213

27. Mad TV (1995–2016)

TV-14 | 60 min | Comedy

A sketch comedy show based on the seminal Mad Magazine.

Stars: Michael McDonald, Debra Wilson, Aries Spears, Bobby Lee

Votes: 11,944

28. Shark Tank (2009– )

TV-PG | 60 min | Family, Game-Show, Reality-TV

Ambitious entrepreneurs present their breakthrough business concepts.

Stars: Kevin O'Leary, Phil Crowley, Mark Cuban, Robert Herjavec

Votes: 10,757

29. Books of Blood (2020)

TV-MA | 107 min | Drama, Horror, Mystery

A journey into uncharted and forbidden territory through three tales tangled in space and time.

Director: Brannon Braga | Stars: Britt Robertson, Freda Foh Shen, Nicholas Campbell, Anna Friel

Votes: 9,933

30. Dexter's Laboratory (1996–2003)

TV-G | 23 min | Animation, Short, Adventure

The misadventures of a boy genius and his annoying sister.

Stars: Kath Soucie, Jeff Bennett, Christine Cavanaugh, Tom Kenny

Votes: 53,875

31. The Loudest Voice (2019)

TV-MA | 50 min | Biography, Drama

The past decade on the life of Roger Ailes, the founder of Fox News, in which Ailes arguably became the Republican party's de facto leader and was accused of sexual harassment, which brought his Fox News reign to an end.

Stars: Russell Crowe, Sienna Miller, Seth MacFarlane, Annabelle Wallis

Votes: 14,528

32. The Cleveland Show (2009–2013)

TV-14 | 22 min | Animation, Adventure, Comedy

Cleveland Brown moves back to his hometown in Virginia, where he finds his high school sweetheart and her two troublemaking kids.

Stars: Mike Henry, Sanaa Lathan, Kevin Michael Richardson, Jason Sudeikis

Votes: 43,067

33. Tooth Fairy (I) (2010)

PG | 101 min | Comedy, Family, Fantasy

A bad deed on the part of a tough minor-league hockey player results in an unusual sentence: He must serve one week as a real-life tooth fairy.

Director: Michael Lembeck | Stars: Dwayne Johnson, Ashley Judd, Julie Andrews, Stephen Merchant

Votes: 49,757 | Gross: $60.02M

34. Flashforward (2009–2010)

TV-14 | 42 min | Drama, Mystery, Sci-Fi

A special task force in the FBI investigates after every person on Earth simultaneously blacks out and awakens with a short vision of their future.

Stars: Courtney B. Vance, Joseph Fiennes, Jack Davenport, Zachary Knighton

Votes: 62,118

35. Real Time with Bill Maher (2003– )

TV-MA | 60 min | Comedy, News, Talk-Show

Comedian and political satirist Bill Maher discusses topical events with guests from various backgrounds.

Stars: Bill Maher, Andrew Sullivan, Michael Moore, Arianna Huffington

Votes: 14,348

36. The View (1997– )

TV-PG | 60 min | Talk-Show

Five women with very different outlooks on politics, Hollywood and its stars, and current events discuss these and other divisive topics of the day. Originated by Barbara Walters and currently led by longtime host, Whoopi Goldberg.

Stars: Whoopi Goldberg, Joy Behar, Virginia Hamilton, Sunny Hostin

Votes: 9,488

37. The Tonight Show Starring Jimmy Fallon (2014– )

TV-14 | 60 min | Comedy, Music, Talk-Show

Jimmy Fallon hosts the Tonight Show and interviews celebrities, plays games with them and has a musical or comedic guest perform.

Stars: Jimmy Fallon, The Roots, Steve Higgins, Questlove

Votes: 19,035

38. The Graham Norton Show (2007– )

TV-14 | 60 min | Comedy, Music, Talk-Show

Irish comedian Graham Norton hosts his very own chat show, which includes chatting to A-list celebrities, the very famous Red Chair game, live music, lots of jokes and fun from Graham and the celebrities themselves.

Stars: Graham Norton, Ricky Gervais, Judi Dench, Jack Whitehall

Votes: 13,217

39. Johnny Bravo (1997–2004)

TV-Y7 | 30 min | Animation, Adventure, Comedy

The misadventures of a dumb blond egomaniac who severely overestimates his own manliness and his supposed "success" with women.

Stars: Jeff Bennett, Brenda Vaccaro, Mae Whitman, Tom Kenny

Votes: 39,365

40. Jimmy Kimmel Live! (2003– )

TV-14 | 60 min | Comedy, Music, Talk-Show

Jimmy Kimmel interviews celebrities.

Stars: Jimmy Kimmel, Cleto and the Cletones, Guillermo Rodriguez, Paul E. Raff

Votes: 17,450

41. May the 12th Be with You (2024)

TV-G | 5 min | Animation, Short, Comedy

In honor of Star Wars Day and Mother's Day, Marge Simpson takes the Disney+ mothers and their children for an adventure.

Director: David Silverman | Stars: Dan Castellaneta, Julie Kavner, Chris Edgerly, Tress MacNeille

Votes: 314

42. CollegeHumor Originals (2006–2023)

TV-14 | Comedy

Funny sketches with crude, adult, and undeniably hilarious comedy.

Stars: Mike Trapp, Grant O'Brien, Katie Marovitch, Zac Oyama

Votes: 1,592

43. Conan (2010–2021)

TV-14 | 42 min | Comedy, Music, Talk-Show

Conan O'Brien and his co-host Andy Richter discuss current news topics and interview celebrities and personalities.

Stars: Conan O'Brien, Andy Richter, Jimmy Vivino and the Basic Cable Band, Jimmy Vivino

Votes: 25,009

44. Live with Kelly and Mark (1988– )

TV-PG | 61 min | Talk-Show

Kelly Ripa and Mark Consuelos interact with their guests.

Stars: Kelly Ripa, Ryan Seacrest, Michael Gelman, Art Moore

Votes: 2,317

45. The Late Show with Stephen Colbert (2015– )

TV-PG | 41 min | Comedy, Talk-Show

Stephen Colbert took over as host, executive producer and writer of THE LATE SHOW on Tuesday, Sept. 8, 2015. The comedy-variety-talk show is broadcast five nights a week from the Ed Sullivan theater in New York.

Stars: Stephen Colbert, Stay Human, Jon Batiste, Jen Spyra

Votes: 14,927

46. The Drew Barrymore Show (2020– )

TV-G | 60 min | News, Talk-Show

Drew Barrymore presents human-interest stories, celebrity guests, lifestyle segments and field pieces, all driven by her infectious brand of humor and optimism.

Stars: Drew Barrymore, Ross Mathews, Pilar Valdes, Mikel Welch

Votes: 1,020

47. Entertainment Tonight (1981– )

30 min | News, Talk-Show

"Entertainment Tonight" is the #1 syndicated entertainment newsmagazine in the world.

Stars: Kevin Frazier, Nischelle Turner, Matt Cohen, Nancy O'Dell

Votes: 2,772

48. Late Night with Conan O'Brien (1993–2009)

TV-14 | 60 min | Comedy, Music, Talk-Show

Conan O'Brien, a Harvard Lampoon alumnus, hosts this late-night comedy/talk-show, which is often silly and whimsical.

Stars: Conan O'Brien, The Max Weinberg 7, Andy Richter, Joel Godard

Votes: 18,985

49. Late Show with David Letterman (1993–2015)

TV-PG | 60 min | Comedy, Music, Talk-Show

The Late Show with David Letterman is an hour-long weeknight comedy and talk-show broadcast by CBS from the Ed Sullivan Theater on Broadway in New York City.

Stars: David Letterman, Paul Shaffer, Alan Kalter, Biff Henderson

Votes: 14,311

50. The Talk (2010–2024)

TV-14 | 42 min | News, Talk-Show

A weekday gabfest offering a female perspective on the day's headlines.

Stars: Sharon Osbourne, Julie Chen Moonves, Sheryl Underwood, Sara Gilbert

Votes: 2,378